Product Market Fit

Product Market Fit

Startup Playbooks

Y Combinator AI Startup School 2026

30,000 applied. 6,000 got in. Here’s everything they heard.

Guillermo Flor's avatar
Guillermo Flor
Jul 27, 2026
∙ Paid

Last weekend, Y Combinator packed the Chase Center and handed the floor to the people actually building the future of AI.

Over 30,000 founders applied, from 120+ countries. Acceptance rate: under 1%. And the ones who got in? Jensen Huang told them flat out: “If you’re here, you’re gonna make it.”

Two days. Ten stages. Jensen Huang, Sam Altman, Boris Cherny, Jeff Dean, Waymo’s Dmitri Dolgov, and more. each one dropping the kind of insight most people pay years of tuition (or failed startups) to learn.

I sat through all of it, read the notes, the transcripts, and every founder’s live thread, so you don’t have to. Inside you’ll find the key takeaways from these speakers:

  • Garry Tan (President, YC)

  • Jensen Huang (Founder and CEO, NVIDIA)

  • Sam Altman (Co-founder and CEO, OpenAI)

  • Boris Cherny (Head of Claude Code, Anthropic)

  • Jeff Dean (Chief Scientist, Google DeepMind)

  • Dmitri Dolgov (Co-founder and CEO, Waymo)

  • Alexandr Wang (Chief AI Officer at Meta)

  • Patrick Collison (Co-founder and CEO, Stripe)

  • Chelsea Finn (Co-founder, Physical Intelligence)

  • Peter Steipete (OpenClaw)

Let’s get into it!


This issue is available exclusively to paid subscribers!

Paid subscribers unlock the full library: 200+ decks, 10,000+ investors, AI Agent playbooks, and fresh high-signal content every week.

Here’s a good place to start:

🤖 AI Agent Templates
↳ The McKinsey Slide Playbook for Claude — how to build consulting-grade presentations in minutes.

📈 Startup Playbooks
↳ The AI Founders Playbook — lessons from Sequoia, OpenAI, Nvidia, and LangChain on building AI startups from zero.

🎯 The Deck Library
↳ 27 Most Promising AI Startup Pitch Decks Backed by Top Investors — the best-funded AI startups of 2025, slide by slide.

💰 Investor Database & Tools
↳ The Family Office List — 1,000 family offices actively writing cheques. Used by 5,000+ founders raising their round.

Not subscribed yet? Try it free for 7 days and unlock this guide, plus our full premium library:

Get 7-Day Free Trial

We’re already 70,000+ founders and operators inside!

Let’s begin!

User's avatar

Continue reading this post for free, courtesy of Guillermo Flor.

Or purchase a paid subscription.
© 2026 Guillermo Flor · Privacy ∙ Terms ∙ Collection notice
Start your SubstackGet the app
Substack is the home for great culture